Safety / cancer supportive care
Tumor safety and side effects of PBM for cancer-treatment toxicities systematic review
de Pauli Paglioni M, et al. Oral Oncology. 2019.
A systematic review of PBM for cancer-treatment toxicities found no tumor-safety issue in the reviewed supportive-care literature.
Evidence grade
moderate
Effect direction
no-clear-effect
Panel relevance
not-panel-replicable
Key findings
- The review included 27 articles covering supportive-care uses such as oral mucositis, lymphedema, radiodermatitis, and neuropathy.
- Most studies reported no PBM side effects.
- This evidence applies to oncology supportive-care protocols, not to DIY treatment of cancer.
Protocol details
| Wavelengths | Not reported nm |
|---|---|
| Irradiance | Not reported mW/cm2 |
| Fluence | Not reported J/cm2 |
| Session time | Not reported minutes |
| Frequency | Oncology supportive-care protocol-specific |
| Duration | Oncology supportive-care protocol-specific |
| Treatment area | Treatment-toxicity-specific tissues |
| Device type | Clinical PBM devices |
Caveats
- This should never be framed as evidence that PBM treats cancer.
- Active cancer, suspicious lesions, and post-treatment oncology questions require clinician input.