Oral lichen planus
Photodynamic and LLLT for oral lichen planus meta-analysis
Hoseinpour Jajarm H, Asadi R, Bardideh E, et al. Photodiagnosis and Photodynamic Therapy. 2018.
A review found LLLT may be a corticosteroid alternative for symptomatic oral lichen planus, while photodynamic therapy evidence was inconclusive.
Evidence grade
low
Effect direction
positive
Panel relevance
not-panel-replicable
Key findings
- Before-after LLLT studies showed pain and sign-score improvement after treatment.
- Comparisons with corticosteroid therapy showed no pain-score difference between methods.
- Photodynamic therapy evidence for lesion-size improvement was inconclusive.
Protocol details
| Wavelengths | Not reported nm |
|---|---|
| Irradiance | Not reported mW/cm2 |
| Fluence | Not reported J/cm2 |
| Session time | Not reported minutes |
| Frequency | Oral medicine protocol-specific |
| Duration | Varied by trial |
| Treatment area | Oral mucosal lesions |
| Device type | Low-level laser therapy and photodynamic therapy |
Caveats
- Oral lichen planus requires dental/oral medicine diagnosis.
- Photodynamic therapy and LLLT should not be merged into simple red panel claims.