Breast cancer-related lymphedema

LLLT for breast cancer-related lymphedema systematic review and meta-analysis

Smoot B, Chiavola-Larson L, Lee J, et al. Journal of Cancer Survivorship. 2015.

Source

A 2015 meta-analysis found moderate-strength evidence that LLLT reduced arm volume and pain in breast cancer-related lymphedema.

Evidence grade

moderate

Effect direction

positive

Panel relevance

not-panel-replicable

Key findings

  • Nine studies met inclusion criteria.
  • Pooled within-group volume reduction was 75.7 ml after LLLT.
  • Between-group pooled results showed a 90.9 ml greater volume reduction when treatment included LLLT.

Protocol details

WavelengthsNot reported nm
IrradianceNot reported mW/cm2
FluenceNot reported J/cm2
Session timeNot reported minutes
FrequencyClinical lymphedema protocol-specific
DurationVaried by study
Treatment areaUpper limb/axillary lymphedema targets
Device typeLow-level laser therapy

Caveats

  • Lymphedema care is specialized and should not be reduced to home panel instructions.
  • Pain between-group effects were not significant in the limited pain analysis.